Cardiothoracic & vascular anesthesia

Association of chronic poststernotomy pain and health-related quality of life: a prospective cohort study

Can J AnaesthPublished Prospective cohort study

Authors' conclusion

Chronic poststernotomy pain still affects patient recovery at six and 12 months after cardiac surgery. The severity of that pain is poorly correlated with patients' quality of life.

Study context

Population
Patients undergoing cardiac surgery with median sternotomy, September 2020–March 2021response rate 65%
Participants
252 patients
Outcome
Association between CPSP severity and health-related quality of life (Short Form McGill Pain Questionnaire, EQ-5D-5L)
Follow-up
Six months
Methodological detailssingle-centre, Telephone interviews at six and 12 months postoperatively
  • Single-centre
  • Telephone interviews at six and 12 months postoperatively

Main finding

As reported in the abstract

Correlation between pain scores and EQ-5D-5L

Spearman's correlation coefficient (weak)

−0.3

Chronic poststernotomy pain (CPSP) at six months

Twenty-nine percent (72/252)

More than mild pain (score ≥ 2/5) at six months

14%

41/252

Observational data: associations, not effects.

Further findings

Persistent pain at 12 months (among 6-month CPSP respondents)

Responded at 12 months
89% (64/72)
Still reported pain
47% (30/64)

Risk factors for CPSP at six months

Higher pain score on POD 1, history of chronic pain before surgery, and history of depression were risk factors
Intraoperative dexmedetomidine or ketamine infusion associated with reduced risk of CPSP
  • Multivariable regression

Original publication

Association of chronic poststernotomy pain and health-related quality of life: a prospective cohort study. Can J Anaesth. Published 29 February 2024. doi:10.1007/s12630-024-02706-4

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