Perioperative medicine & outcomes
Association of Intraoperative Occult Hypoxemia With 30-Day and 1-Year Mortality
Authors' conclusion
Intraoperative occult hypoxemic events are associated with significantly higher odds of 30-day and 1-year mortality, independent of self-reported race/ethnicity.
Study context
- Population
- Adults (≥18 years) undergoing anesthesia 2008–2019 with at least 1 intraoperative arterial blood gas62,707 paired readings
- Participants
- 25,234 adults
- Exposure
- At least 1 intraoperative occult hypoxemic event vs none
- At least 1 occult hypoxemic eventn = 351
- Outcome
- 30-day and 1-year postoperative mortality
- Follow-up
- 30 days and 1 year
Methodological detailssingle-centre, propensity score overlap-weighted
- Single-centre
- Propensity score overlap-weighted
Main finding
As reported in the abstract
At least 1 occult hypoxemic event vs No occult hypoxemic eventEstimate (95% CI)P value
30-day mortality
OR 2.89(1.46–5.72)
P = 0.0021-year mortality
HR 1.90(1.48–2.43)
P < 0.001Observational data: associations, not effects.
Further findings
Interaction of occult hypoxemia with self-reported race/ethnicity
- No significant interaction for predicting mortality
Original publication
Association of Intraoperative Occult Hypoxemia With 30-Day and 1-Year Mortality. Anesth Analg. Published 4 February 2025. doi:10. 1213/ ane. 0000000000007405
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