Association of Omega-3 Status With Long-Term Risk of Hospitalization for Sepsis
Authors' conclusion
In this population-based cohort study, baseline eO3I was inversely associated with subsequent sepsis incidence.
Study context
- Population
- UK Biobank participantsUK Biobank
- Participants
- 273,325 participants
- Exposure
- Higher vs lowest baseline estimated omega-3 index quartile
- Outcome
- Sepsis incidence
- Follow-up
- Mean 13 years
Methodological detailsretrospective
- Retrospective
Main finding
As reported in the abstract
Hazard ratio (95% CI)P value
Q2 vs Q1
0.88(0.86–0.91)
P < 0.001Q3 vs Q1
0.80(0.78–0.83)
P < 0.001Q4 vs Q1
0.75(0.73–0.77)
P < 0.001- Participants hospitalised with sepsis
- 9241
- Increasing eO3I (continuous) associated with decreasing sepsis risk
- P < 0.001
Observational data: associations, not effects.
Further findings
- Median (IQR) baseline eO3I
- 6.0% (4.8-7.3%)
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Association of Omega-3 Status With Long-Term Risk of Hospitalization for Sepsis. Crit Care Med. Published 3 February 2025. doi:10. 1097/ ccm. 0000000000006593
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