Respiratory failure & ventilation
Association of plasma volume status with outcomes in hospitalized Covid-19 acute respiratory distress syndrome (ARDS) patients: A retrospective multicenter observational study
Authors' conclusion
A lower PVS on admission correlated with a greater chance of survival in COVID-19-related ARDS patients.
Study context
- Population
- COVID-19-related ARDS patients (sequential organ failure assessment (SOFA) respiratory score ≥ 2, PaO2/FiO2 ≤300 mmHg) admitted to the Mayo Clinic Enterprise health system
- Participants
- 1,298 patients
- Exposure
- Plasma volume status and estimated plasma volume on admission
- Outcome
- 90-day mortality
- Follow-up
- 90 days
Methodological detailsmulticentre, observational
- Multicentre
- Observational
Main finding
As reported in the abstract
Hazard ratio (95% CI)P value
PVSCox multivariate, adjusted for covariates; independent association
1.015(1.005–1.025)
P = 0.002ePVCox multivariate, adjusted for covariates; not independent
1.054(0.958–1.159)
P = 0.278- Mortality rate
- 25.96%
Observational data: associations, not effects.
Original publication
Association of plasma volume status with outcomes in hospitalized Covid-19 ARDS patients: A retrospective multicenter observational study. J Crit Care. Published 20 July 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →