Perioperative medicine & outcomes
Association of preoperative smoking with the occurrence of postoperative pulmonary complications: A post hoc analysis of an observational study in 29 countries
Authors' conclusion
The occurrence of PPCs in smokers is not different from non-smokers.
Study context
- Population
- Surgical patients at increased risk of postoperative pulmonary complications (PPCs) (ARISCAT score ≥ 26 points), 146 hospitals in 29 countries
- Participants
- 531 vs 2,102
- Comparison
- Smokers vs non-smokers
- Smokersn = 531
- Non-smokersn = 2,102reference
- Primary endpoint
- One or more predefined PPCs (unplanned supplementary oxygen, respiratory failure, unplanned invasive ventilation, ARDS, pneumonia, pneumothorax)
- Follow-up
- First five postoperative days
Methodological detailspropensity score matching, multicentre
- Propensity score matching
- Multicentre
Primary result
As reported in the abstract
5 days after surgery
Smokers
19.0 %
101 of 531
Non-smokers
19.2
404 of 2102
P = 0.95
Secondary outcomes
Respiratory failure
P = 0.02
Other PPCs (supplementary oxygen, invasive ventilation, ARDS, pneumonia, pneumothorax)
- Did not differ between the groups
Hospital LOS and mortality
- Not different between groups
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Association of preoperative smoking with the occurrence of postoperative pulmonary complications: A post hoc analysis of an observational study in 29 countries. J Clin Anesth. Published 14 May 2025. doi:10.
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