ICU sedation, delirium & recovery
Associations Between Family-Assessed Quality-of-Dying-and-Death Latent Classes and Bereavement Outcomes for Family Surrogates of ICU Decedents*
Authors' conclusion
The four distinct QODD latent classes were significantly associated with ICU family surrogates' bereavement outcomes
Study context
- Population
- Family surrogates responsible for decision-making for critically ill patients at high risk of death (APACHE II scores > 20), medical ICUs at two academically affiliated medical centers in Taiwan
- Participants
- 309 participants
- Exposure
- Moderate, poor-to-uncertain and worst vs high quality of dying and death (QODD) latent classes
- Outcome
- Depressive symptoms, mental HRQOL, anxiety and PTSD symptoms (β vs high QODD class)
- Follow-up
- Over 24 bereavement months
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
- Moderate
- β (depressive symptoms) 1.958 (95% CI 1.144–2.772)
- Poor-to-uncertain
- β (depressive symptoms) 2.224 (95% CI 1.438–3.010)
- Worst
- β (depressive symptoms) 2.081 (95% CI 1.215–2.964)
- Moderate
- β (mental health-related quality of life (HRQOL)) −2.245 (95% CI −3.961 to −0.529)
- Poor-to-uncertain
- β (mental HRQOL) −7.026 (95% CI −8.683 to −5.369)
- Worst
- β (mental HRQOL) −4.268 (95% CI −6.096 to −2.440)
- Moderate
- β (anxiety symptoms) 2.095 (95% CI 1.392–2.798)
- Poor-to-uncertain
- β (anxiety symptoms) 0.801 (95% CI 0.123–1.480)
- Poor-to-uncertain
- β (post-traumatic stress disorder (PTSD) symptoms) 2.889 (95% CI 1.005–4.774)
Observational data: associations, not effects.
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Associations Between Family-Assessed Quality-of-Dying-and-Death Latent Classes and Bereavement Outcomes for Family Surrogates of ICU Decedents*. Crit Care Med. Published 1 February 2024. doi:10.
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