ICU sedation, delirium & recovery
ICU Bereaved Surrogates’ Transition Through States of Co-Occurring Prolonged Grief Disorder, Posttraumatic Stress Disorder, and Depression Symptoms*
Authors' conclusion
Four highly stable PGD-PTSD-depression-symptom states were identified, highlighting the importance of screening for subgroups of ICU bereaved surrogates with increased PGD or comorbid PGD, PTSD, and depression symptoms during early bereavement.
Study context
- Population
- Family surrogates responsible for decision-making for critically ill patients at high risk of death (APACHE II > 20), medical ICUs at two academically affiliated medical centers in Taiwan
- Participants
- 303 participants
- Exposure
- Resilient vs Subthreshold depression-dominant vs prolonged grief disorder (PGD)-dominant vs PGD-PTSD-depression comorbid
- Outcome
- Transition of PGD-PTSD-depression-symptom states (PG-13 11 items, Impact of Event Scale-Revised, HADS depression subscale)
- Follow-up
- 6, 13, 18, and 24 months postloss
Methodological detailslatent transition analysis, two centres
- Latent transition analysis
- Two centres
Main finding
As reported in the abstract
Initial prevalence of symptom states
Observational data: associations, not effects.
Further findings
Prevalence of each symptom state (resilient, subthreshold depression-dominant, PGD-dominant, PGD-PTSD-depression comorbid, respectively) · 24 months postloss
- Resilient, subthreshold depression-dominant, PGD-dominant, PGD-PTSD-depression comorbid states, respectively
- 82.1%, 11.4%, 4.0%, and 2.5%
- States remained highly stable over the first two bereavement years, with transitions predominantly toward resilience
Original publication
ICU Bereaved Surrogates’ Transition Through States of Co-Occurring Prolonged Grief Disorder, Posttraumatic Stress Disorder, and Depression Symptoms*. Crit Care Med. Published 28 April 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →