ICU sedation, delirium & recovery

Predictors of ICU Surrogates’ States of Concurrent Prolonged Grief, Posttraumatic Stress, and Depression Symptoms*

Crit Care MedPublished Prospective cohort study

Authors' conclusion

Surrogates' concurrent bereavement distress was positively associated with clinically modifiable factors: poor quality dying and death, higher surrogate anxiety, and palliative care-commonly provided late in the terminal-illness trajectory worldwide. Social-worker involvement and a do-not-resuscitate order appeared to mitigate risk.

Study context

Population
Family surrogates of patients in medical ICUs of two Taiwanese medical centers
Participants
288 family surrogates
Exposure
Risk factors across four PGD-PTSD-depressive-symptom states
Outcome
Factors associated with four PGD-PTSD-depressive-symptom states (multinomial logistic regression)
Methodological detailsmulticentre
  • Multicentre

Main finding

As reported in the abstract

Factors associated with symptom states vs resilient state
Each group vs resilientAdjusted odds ratio (95% CI)
PGD-PTSD-depression concurrentprovision of palliative care
8.750(1.603–47.768)
Subthreshold depression-dominantpoor-to-uncertain perceived quality of dying and death
4.063(1.531–10.784)
PGD-PTSD-depression concurrentpoor-to-uncertain perceived quality of dying and death
12.833(1.231–133.775)
PGD-PTSD-depression concurrentworst perceived quality of dying and death
12.820(1.806–91.013)
PGD-PTSD-depression concurrentsocial-worker involvement
0.004(0.001–0.097)
Subthreshold depression-dominantdo-not-resuscitate order issued before death
0.177(0.032–0.978)
Three more profound distress states · higher anxiety symptoms
aOR 1.781 to 2.768 (95% CI 1.562-2.031 to 2.288-3.347)

Observational data: associations, not effects.

Original publication

Predictors of ICU Surrogates’ States of Concurrent Prolonged Grief, Posttraumatic Stress, and Depression Symptoms*. Crit Care Med. Published 11 September 2024. doi:10.1097/ccm.0000000000006416

Composed by AI from the published abstract and checked against it. How Briefs are made →

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