ICU sedation, delirium & recovery

An augmented rehabilitation package incorporating immersive virtual reality during early recovery after acute respiratory distress syndrome (ARDS): A randomized controlled trial

Ann Intensive CarePublished Randomised controlled trial

Primary result · MoCA scoreResult — go to the resultAdjusted between-group effect 1.42 95% CI 0.86–1.98

Authors' conclusion

An augmented rehabilitation package incorporating immersive VR was associated with short-term improvements in cognition, health-related quality of life, and anxiety symptoms during early ARDS recovery.

Study context

Population
ARDS patients in the rehabilitation phase87 analysed
Participants
88 patients
Comparison
Virtual reality (VR) vs Control
  • VRn = 44
  • Controln = 44reference
Primary endpoint
Change in Montreal Cognitive Assessment (MoCA) score from baseline
Follow-up
4 weeks
Methodological detailssingle-center, parallel-group, 1:1 randomization, available-case analysis, analysis of covariance (ANCOVA) adjusted for baseline score, retrospectively registered, Control condition not time- or attention-matched
  • Single-center
  • Parallel-group
  • 1:1 randomization
  • Available-case analysis
  • ANCOVA adjusted for baseline score
  • Retrospectively registered
  • Control condition not time- or attention-matched

Primary result

MoCA score

Adjusted between-group effect

1.42

95% CI 0.86–1.98

P < 0.001

As reported in the abstract

Secondary outcomes

OutcomeVRAdjusted effect (95% CI)P value
SF-36 score13.20 (11.85–14.54)P < 0.001
HADS-A score−2.55 (−3.23 to −1.88)P < 0.001
Satisfaction with intervention (very satisfied or satisfied)65.9%

Original publication

An augmented rehabilitation package incorporating immersive virtual reality during early recovery after ARDS: A randomized controlled trial. Ann Intensive Care. Published 8 September 2026. doi:10.1016/j.aicoj.2026.100154

Composed by AI from the published abstract and checked against it. How Briefs are made →

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