ICU sedation, delirium & recovery

Impact of ICU and post-ICU interventions on the psychological dimensions of patients' Post-Intensive Care Syndrome (PICS): A systematic review with narrative synthesis

J Crit CarePublished Systematic review with narrative synthesis

Authors' conclusion

Narrative and multimodal interventions showed the most consistent signals of benefits, particularly for PTSD, depression, and HRQoL, although evidence often came from studies with methodological limitations.

Study context

Population
ICU survivors39 studies
Participants
8 / 6 / 2 / 10 / 1 / 1 / 11
Comparison
ICU and post-ICU interventions for psychological dimensions of PICS
  • Physicaln = 8
  • Self-management education strategiesn = 6
  • Evaluative follow-upn = 2
  • Narrativen = 10
  • EMDRn = 1
  • ICU simulation with virtual realityn = 1
  • Multimodal interventionsn = 11
Outcome
HRQoL, anxiety, depression and PTSD symptoms
Methodological detailsPRISMA, quantitative, qualitative and mixed-methods designs eligible, RoB 2, ROBINS-I V2 and MMAT quality assessment, 3494 records identified; five databases searched
  • PRISMA
  • Quantitative, qualitative and mixed-methods designs eligible
  • RoB 2, ROBINS-I V2 and MMAT quality assessment
  • 3494 records identified; five databases searched

Pooled result

As reported in the abstract

Psychological outcomes

Studies reporting improvement in at least one psychological outcome

14

Studies reporting no benefit

23

Evaluative interventions associated with worse outcomes

2

Original publication

Impact of ICU and post-ICU interventions on the psychological dimensions of patients' PICS: A systematic review with narrative synthesis. J Crit Care. Published 18 June 2026. doi:10.1016/j.jcrc.2026.155658

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