ICU sedation, delirium & recovery

Optimal timing for assessing post-intensive care syndrome in clinical research: a scoping review and expert survey

J Intensive CarePublished Scoping review and expert survey

Authors' conclusion

This study revealed notable discrepancies between the assessment timing reported in previous studies and the opinions of experts regarding optimal timing.

Study context

Population
Studies assessing post-intensive care syndrome (PICS)-related outcomes (physical, cognitive, psychological impairments; PICS in family members) and PICS experts657 studies
Participants
657 vs 23
Exposure
Assessment timing in prior PICS studies vs expert opinion
  • Prior studiesn = 657
  • Expertsn = 23
Outcome
Reference point for assessment schedule, assessment time points, and their frequency
Methodological detailsonline questionnaire, Databases: MEDLINE, CENTRAL, CINAHL; screened by two independent pairs of reviewers
  • Online questionnaire
  • Databases: MEDLINE, CENTRAL, CINAHL; screened by two independent pairs of reviewers

Main finding

As reported in the abstract

Most common reference point in prior studies: hospital discharge (240 studies)
40%
Ideal reference point per experts: ICU discharge (16 votes)
47%
Most frequent time point in prior studies: 3 months post-discharge (262)
23%
Time point in prior studies: 6 months post-discharge (212)
19%
Time point in prior studies: 12 months post-discharge (206)
18%
Single assessment most common in prior studies (337)
51%
Ideal per experts: three assessments (12)
44%

Observational data: associations, not effects.

Original publication

Optimal timing for assessing post-intensive care syndrome in clinical research: a scoping review and expert survey. J Intensive Care. Published 18 August 2025. doi:10.1186/s40560-025-00817-8

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