Neuroanesthesia & neurocritical care
Awake burr hole craniotomy for chronic subdural hematoma: a phase 2 randomized controlled trial
Authors' conclusion
LA was associated with significantly lower rates of postoperative delirium and a shorter periprocedural duration compared to GA in patients undergoing cSDH evacuation.
Study context
- Population
- Consecutive patients with confirmed chronic subdural hematoma (cSDH) undergoing burr hole craniotomy, tertiary academic centre, October 2023–November 2024
- Participants
- 50 consecutive patients
- Comparison
- Burr hole craniotomy under local anesthesia (LA) vs general anesthesia (GA)
- Primary endpoint
- Postoperative delirium (CAM) and complication rates until discharge, and recruitment rate
- Follow-up
- Until discharge
Methodological detailssingle-centre, open-label, phase 2, prospective
- Single-centre
- Open-label
- Phase 2
- Prospective
Original publication
Awake burr hole craniotomy for chronic subdural hematoma: a phase 2 randomized controlled trial. Crit Care. Published 9 March 2026. doi:10.
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