Neuroanesthesia & neurocritical care
Local anesthesia versus general anesthesia for surgical drainage of chronic subdural hematoma: a systematic review and meta-analysis
Pooled result · Low certainty of evidenceResult — go to the resultMean difference (LOS) about two days days 95% CI −3.47 to −0.77Authors' conclusion
Local anesthesia with/without sedation for surgical drainage of CSDH may be associated with a shorter LOS, and lower postoperative complications.
Study context
- Population
- Adults undergoing surgical drainage of chronic subdural hematoma (CSDH)8 studies (2 randomized controlled trials (RCTs), 6 observational)
- Participants
- 1,542 adults
- Comparison
- LA vs general anesthesia (GA) for surgical drainage of chronic subdural hematoma
- LAn = 926
- GAn = 616reference
- Outcome
- Total duration of surgery, recurrence rate, and LOS
Methodological detailsRCTs and observational studies, Observational studies' quality poor to fair; of the RCTs, one low and one high risk of bias
- RCTs and observational studies
- Observational studies' quality poor to fair; of the RCTs, one low and one high risk of bias
Pooled result
Low certainty of evidence
Mean difference (LOS)
about two days days
95% CI −3.47 to −0.77
P = 0.01
As reported in the abstract
Safety
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| Postoperative complicationsVery low certainty of evidence | 0.31 (0.17–0.58) | P = 0.004 | |
| 0.10.31310Odds ratio (log scale) |
Intraoperative adverse events and mortality
- No significant difference
Original publication
Local anesthesia versus general anesthesia for surgical drainage of chronic subdural hematoma: a systematic review and meta-analysis. Can J Anaesth. Published 28 February 2024. doi:10.
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