Cardiac arrest & resuscitation

Barriers to bystander interventions in suspected opioid-associated out-of-hospital cardiac arrests: A multiple methods study of 9-1-1 calls

ResuscitationPublished Retrospective multiple methods study

Authors' conclusion

We found significant differences in demographics between suspected OA-OHCA compared with non-suspected OA-OHCA. We also identified unique barriers in this population as well as previously described barriers which may be amplified in the setting of suspected drug use.

Study context

Population
Adult, non-traumatic OHCA with transcribed 9–1–1 calls, two North Carolina counties, 5/2022–12/2023
Exposure
Suspected opioid-associated out-of-hospital cardiac arrests (OA-OHCA) vs non-suspected OA-OHCA
Outcome
Characteristics of 9-1-1 callers and patients in suspected OA-OHCA; barriers to bystander CPR and naloxone administration
Methodological detailstranscribed 9-1-1 calls, two counties in North Carolina
  • Transcribed 9-1-1 calls
  • Two counties in North Carolina

Main finding

As reported in the abstract

Caller and patient characteristics; barriers to bystander CPR and naloxone

In a residence

OutcomeSuspected OA-OHCANon-suspected OA-OHCAP value
Age39 years58 yearsP < 0.01
Caller a friend35 %— not stated in the abstract
Caller a family member— not stated in the abstract34 %

— not stated in the abstract

  • Suspected OA-OHCA vs Non-suspected OA-OHCA: P < 0.01 — location in a residence
  • Suspected OA-OHCA vs Non-suspected OA-OHCA: P < 0.01 — caller relationship

Observational data: associations, not effects.

Original publication

Barriers to bystander interventions in suspected opioid-associated out-of-hospital cardiac arrests: A multiple methods study of 9-1-1 calls. Resuscitation. Published 5 August 2025. doi:10.1016/j.resuscitation.2025.110748

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