ICU sedation, delirium & recovery

Based -evidence, an intervention study to improve sleep quality in awake adult intensive care unit (ICU) patients: a prospective, single-blind, clustered controlled trial

Crit CarePublished Nonrandomised cluster controlled trial

Authors' conclusion

Evidence-based interventions significantly improve sleep quality in ICU patients hospitalized for more than one day. However, our results do not support the improvement of sleep quality in patients admitted to the ICU for one day.

Study context

Population
Conscious adults (≥18 years) staying ≥1 night in two intensive care units (ICUs) of a tertiary teaching hospital in Chinaincluded in the analysis
Participants
246 adults
Exposure
Evidence-based sleep interventions vs control
  • Interventionn = 125
  • Controln = 121reference
Outcome
Sleep quality (actigraphy: total, deep, light and REM sleep time, awakenings, overall sleep score; RCSQ self-assessment)
Methodological detailsprospective, single-blind (patients only), nonrandomized, single-centre (two ICUs), Outcome assessors not blinded, Retrospectively registered, September 1, 2023, to January 31, 2024; 713 assessed for eligibility
  • Prospective
  • Single-blind (patients only)
  • Nonrandomized
  • Single-centre (two ICUs)
  • Outcome assessors not blinded
  • Retrospectively registered
  • September 1, 2023, to January 31, 2024; 713 assessed for eligibility

Main finding

As reported in the abstract

Sleep quality, ICU stay = 1 night
GroupValueRichards-Campbell Sleep Questionnaire (RCSQ) scoreTotal sleep timeAwakening frequency
Intervention57.74 ± 22.5560.58 ± 22.14440.42 ± 262.113.98 ± 2.69
Control57.72 ± 19.3957.61 ± 24.4420.31 ± 236.896.09 ± 4.66

Value

Intervention57.74 ± 22.55
Control57.72 ± 19.39

Richards-Campbell Sleep Questionnaire (RCSQ) score

Intervention60.58 ± 22.14
Control57.61 ± 24.4

Total sleep time

Intervention440.42 ± 262.11
Control420.31 ± 236.89

Awakening frequency

Intervention3.98 ± 2.69
Control6.09 ± 4.66
  • Intervention vs Control: P > 0.05 — no statistically significant differences; small effect size

Observational data: associations, not effects.

Further findings

Sleep quality, ICU stay > 1 night (pre-post analysis)

Significant improvement in all parameters except rapid eye movement (REM) time; medium to large effect size
P < 0.05

Original publication

Based -evidence, an intervention study to improve sleep quality in awake adult ICU patients: a prospective, single-blind, clustered controlled trial. Crit Care. Published 12 November 2024. doi:10.1186/s13054-024-05161-1

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