Respiratory failure & ventilation

Bedside electrical impedance tomography in early diagnosis of pneumothorax in mechanically ventilated intensive care unit (ICU) patients — a single-center retrospective cohort study

J Clin Monit ComputPublished Retrospective cohort study

Authors' conclusion

The ventilation defect in the ventral regions and a high HVVI on EIT were observed in mechanically ventilated patients with PTX, which should trigger further diagnostics to confirm it.

Study context

Population
Mechanically ventilated supine ICU patients who received electrical impedance tomography (EIT) examinations
Participants
203 participants
Exposure
Pneumothorax (PTX) vs no PTX on bedside EIT
  • PTXn = 25
Outcome
EIT ventilation defect score (DS) and horizontal ventral ventilation index (HVVI)
Methodological detailssingle-center
  • Single-center

Main finding

As reported in the abstract

GroupValueDefect score (DS) dorsal quadrants, median (IQR)Horizontal ventral ventilation index (HVVI), median (IQR)
PTXmedian 1.00 (IQR 0.00–2.00)1.00 (0.00, 1.00)2.51 (1.58, 3.52)
non-PTXmedian 0.00 (IQR 0.00–0.00)0.00 (0.00, 1.00)1.36 (1.15, 1.77)

Value

PTXmedian 1.00 (IQR 0.00–2.00)
non-PTXmedian 0.00 (IQR 0.00–0.00)

Defect score (DS) dorsal quadrants, median (IQR)

PTX1.00 (0.00, 1.00)
non-PTX0.00 (0.00, 1.00)

Horizontal ventral ventilation index (HVVI), median (IQR)

PTX2.51 (1.58, 3.52)
non-PTX1.36 (1.15, 1.77)
  • PTX vs non-PTX: P < 0.001 — DS ventral quadrants
  • PTX vs non-PTX: P = 0.722 — DS dorsal quadrants, similar
  • PTX vs non-PTX: P < 0.001 — HVVI higher in PTX

Observational data: associations, not effects.

Further findings

OutcomeValues
Diagnostic accuracy of HVVI for PTX vs non-PTXHVVI AUC 0.88 · sensitivity 70% · specificity 90% · cut-off 2.57

Cause of PTX

Preceding cardiac surgery was the most common cause of PTX

Original publication

Bedside electrical impedance tomography in early diagnosis of pneumothorax in mechanically ventilated ICU patients — a single-center retrospective cohort study. J Clin Monit Comput. Published 4 November 2022. doi:10.1007/s10877-022-00935-w

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