Behind the scenes: Key lessons learned from the RELIEVE-AKI clinical trial
Study context
- Population
- Critically ill patients with severe AKI undergoing continuous kidney replacement therapy (CKRT)
- Comparison
- Restrictive vs liberal net ultrafiltration rate during CKRT
Methodological detailsICU-based, dynamically titrated intervention
- ICU-based
- Dynamically titrated intervention
Primary result
As reported in the abstract
Challenges and solutions in implementing the trial
- Challenges: rapidly changing hemodynamics, low recruitment rates, increased nursing workload, enormous data volume from prolonged CKRT
- Solutions: streamline the intervention, more flexible protocols, comprehensive a priori planning (nursing roles and compensation), enhanced data management systems
Original publication
Behind the scenes: Key lessons learned from the RELIEVE-AKI clinical trial. J Crit Care. Published 15 June 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →