Bilateral ultrasound-guided maxillary and mandibular combined nerves block reduces morphine consumption after double-jaw orthognathic surgery: a randomized controlled trial
Primary result · Cumulative OME consumptionResult — go to the resultMean difference −20.1 mg 95% CI −37.4 to −2.9Authors' conclusion
Bilateral ultrasound-guided V2 and V3 combined nerves block reduces postoperative opioid consumption by about 50% in patients undergoing double-jaw surgery.
Study context
- Population
- Patients undergoing double-jaw orthognathic surgery
- Participants
- 50 patients
- Comparison
- V2 and V3 block vs Infiltration
- Primary endpoint
- Cumulative oral morphine equivalent (OME) consumption
- Follow-up
- POD 1
Methodological detailssingle-blind, prospective
- Single-blind
- Prospective
Primary result
Cumulative OME consumption · Day 1
Mean difference
−20.1 mg
95% CI −37.4 to −2.9
P = 0.023
By group
V2 and V3 block vs Infiltration
mean difference −20.1 mg (95% CI −37.4 to −2.9); P = 0.023
As reported in the abstract
Secondary outcomes
Mean, mg
| Outcome | V2 and V3 block | Infiltration | Mean difference (mg) (95% CI) | P value | |
|---|---|---|---|---|---|
| Cumulative OME consumption · Day 2 | 35.8 (SD 30.2) | 64.5 (SD 60) | −28.7 (−55.9 to −1.43) | P = 0.040 | |
| −100−50050Difference, mg (linear scale) |
Correlation of preoperative anxiety (Amsterdam Preoperative Anxiety and Information Scale (APAIS)) with worst pain score and cumulative oral morphine equivalent (OME) consumption on day 2
- Worst pain score vs APAIS, Pearson's correlation coefficient (p=0.003)
- 0.42
- Cumulative OME consumption vs APAIS, Pearson's correlation coefficient (p=0.006)
- 0.39
Original publication
Bilateral ultrasound-guided maxillary and mandibular combined nerves block reduces morphine consumption after double-jaw orthognathic surgery: a randomized controlled trial. Reg Anesth Pain Med. Published 2 May 2024. doi:10.
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