Efficacy of anterior subcostal quadratus lumborum block for postoperative analgesia in laparoscopic colorectal surgery: a randomized controlled trial
Authors' conclusion
The anterior subcostal QLB was associated with reduced postoperative opioid use, lower pain scores and a lower incidence of postoperative nausea-vomiting after LCS
Study context
- Population
- Adults scheduled for elective laparoscopic colorectal surgery at a university hospital, October 2024–May 202555 analysed
- Participants
- 60 adults
- Comparison
- Quadratus lumborum block (QLB) vs control
- QLBn = 27
- Controln = 28reference
- Primary endpoint
- Cumulative IV MME consumption
- Follow-up
- 24 hours postoperatively
Methodological detailsprospective, observer-blinded, single-centre
- Prospective
- Observer-blinded
- Single-centre
Primary result
As reported in the abstract
24-hour IV MME consumption · 24 hours
P = 0.006
Secondary outcomes
Time to first PCA demand · prolonged
P < 0.001
Rescue analgesia
Antiemetic use
Time to mobilization
P = 0.026
Hospital LOS
P = 0.008
| Outcome | P value |
|---|---|
| Pain scores (rest and activity), all time pointsSignificantly lower in the QLB group | P < 0.001 |
Safety
Antiemetic use
Block-related complications
- No block-related complications observed
Original publication
Efficacy of anterior subcostal quadratus lumborum block for postoperative analgesia in laparoscopic colorectal surgery: a randomized controlled trial. Reg Anesth Pain Med. Published 28 October 2025. doi:10.
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