The effect of anterior quadratus lumborum block on morphine consumption in minimally invasive colorectal surgery: a multicentre, double‐blind, prospective randomised placebo‐controlled trial
Authors' conclusion
In laparoscopic colorectal surgery, adding a bilateral anterior quadratus lumborum block to a standard multimodal analgesia regimen did not reduce opioid consumption or improve pain scores.
Study context
- Population
- Patients undergoing laparoscopic colorectal surgery (left- or right hemicolectomy, sigmoidectomy) in an institutional abdominal enhanced recovery programme
- Participants
- 150 patients
- Comparison
- Bilateral anterior QL block with ropivacaine 0.375% vs placebo
- Ropivacainen = 75
- Placebon = 75reference
- Primary endpoint
- Morphine consumption
- Follow-up
- First 24 h after tracheal extubation
Methodological detailstwo-centre, double-blind, prospective, placebo-controlled
- Two-centre
- Double-blind
- Prospective
- Placebo-controlled
Primary result
As reported in the abstract
24-hour morphine consumption · 24 h
P = 0.966
Secondary outcomes
Sensory block
- Detected in significantly more patients in the ropivacaine group
Pain scores and other secondary endpoints
- No differences detected
Patient satisfaction
- High in both groups
Safety
Safety endpoints (incl. adverse events)
- No differences detected
Original publication
The effect of anterior quadratus lumborum block on morphine consumption in minimally invasive colorectal surgery: a multicentre, double‐blind, prospective randomised placebo‐controlled trial. Anaesthesia. Published 16 November 2023. doi:10.
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