Cardiac arrest & resuscitation
Blood laboratory analyses preceding in‐hospital cardiac arrest: A matched case–control study
Authors' conclusion
Patients with IHCA undergo more frequent blood sampling prior to IHCA and have higher levels of lactate compared to matched controls.
Study context
- Population
- Hospitalised patients in Denmark, 2017–2021
- Participants
- 9,268 vs 92,395
- Comparison
- Patients with in-hospital cardiac arrest (IHCA) vs matched hospitalised controls
- Casesn = 9,268
- Controlsn = 92,395reference
- Outcome
- Pre-arrest sampling frequencies, results and trends of lactate, sodium, potassium and haemoglobin
- Follow-up
- Last 24 h before the index time
Methodological detailsnational registries
- National registries
Main finding
As reported in the abstract
Last measured lactate · within 24 h before index time
Cases
2.3
median · IQR 1.3–4.9
Controls
1.3
median · IQR 0.9–2.0
Observational data: associations, not effects.
Further findings
Temporal trends before index time
- Proportion of abnormally elevated lactate and potassium increased as time to cardiac arrest decreased in cases; no such effect in controls
- No temporal trend for sodium or haemoglobin
Original publication
Blood laboratory analyses preceding in‐hospital cardiac arrest: A matched case–control study. Acta Anaesthesiol Scand. Published 23 May 2024. doi:10.
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