Cardiac arrest & resuscitation

Potassium Levels and In-Hospital Cardiac Arrest: A Matched Case-Control Study

Crit Care MedPublished Registry-based matched case-control study

Authors' conclusion

Hyperkalemia was associated with an increased risk of in-hospital cardiac arrest and with worse outcomes after cardiac arrest. Hypokalemia was associated with an increased risk of in-hospital cardiac arrest but was not associated with outcomes after cardiac arrest.

Study context

Population
Hospitalized adults in Denmark, 2017 to 2021
Comparison
Pre-arrest hyperkalemia or hypokalemia vs normokalemia
  • Casesn = 6,658
  • Controlsn = 49,906reference
Outcome
Odds of IHCA
Methodological detailsmatched on age, sex, and length and time of admission
  • Matched on age, sex, and length and time of admission

Main finding

As reported in the abstract

Odds

2.03

95% CI 1.28–3.23

Severe hyperkalemia vs Normokalemia

Odds

2.65

95% CI 1.61–4.38

Severe hypokalemia vs Normokalemia

Observational data: associations, not effects.

Further findings

ROSC, 30-day survival and 1-year survival after IHCA

Increasing severity of hyperkalemia associated with decreased odds of ROSC, 30-day survival and 1-year survival
No clear association between hypokalemia and these outcomes

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Potassium Levels and In-Hospital Cardiac Arrest: A Matched Case-Control Study. Crit Care Med. Published 19 May 2025. doi:10.1097/ccm.0000000000006713

Composed by AI from the published abstract and checked against it. How Briefs are made →

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