Cardiac arrest & resuscitation
Potassium Levels and In-Hospital Cardiac Arrest: A Matched Case-Control Study
Authors' conclusion
Hyperkalemia was associated with an increased risk of in-hospital cardiac arrest and with worse outcomes after cardiac arrest. Hypokalemia was associated with an increased risk of in-hospital cardiac arrest but was not associated with outcomes after cardiac arrest.
Study context
- Population
- Hospitalized adults in Denmark, 2017 to 2021
- Comparison
- Pre-arrest hyperkalemia or hypokalemia vs normokalemia
- Casesn = 6,658
- Controlsn = 49,906reference
- Outcome
- Odds of IHCA
Methodological detailsmatched on age, sex, and length and time of admission
- Matched on age, sex, and length and time of admission
Main finding
As reported in the abstract
Odds
2.03
95% CI 1.28–3.23
Severe hyperkalemia vs Normokalemia
Odds
2.65
95% CI 1.61–4.38
Severe hypokalemia vs Normokalemia
Observational data: associations, not effects.
Further findings
ROSC, 30-day survival and 1-year survival after IHCA
- Increasing severity of hyperkalemia associated with decreased odds of ROSC, 30-day survival and 1-year survival
- No clear association between hypokalemia and these outcomes
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
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