Cardiac arrest & resuscitation
Vital signs preceding in-hospital cardiac arrest: a matched case-control study
Authors' conclusion
The risk of in-hospital cardiac arrest increases incrementally with the degree of vital sign abnormality.
Study context
- Population
- Hospitalised patients, Central Denmark Region, 2017–2022
- Participants
- 1,587 vs 10,276
- Comparison
- Vital sign values vs normal reference values
- Casesn = 1,587
- Controlsn = 10,276reference
- Outcome
- Association between vital signs and risk of in-hospital cardiac arrest
Methodological detailsregistry-based
- Registry-based
Main finding
As reported in the abstract
Risk of in-hospital cardiac arrest
Odds ratio (95 % CI)
SBP ≤80 mmHg vs normal reference values
15.3(9.44–24.7)
SpO2/FiO2 ≤ 2.50 vs normal reference values
14.1(10.3–19.2)
NEWS 2 score ≥7 points vs normal reference values
11.7(9.57–14.3)
Observational data: associations, not effects.
Original publication
Vital signs preceding in-hospital cardiac arrest: a matched case-control study. Resuscitation. Published 14 August 2025. doi:10.
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