Perioperative medicine & outcomes

Bone cement implantation syndrome: a scoping review

Br J AnaesthPublished Scoping review

Authors' conclusion

Bone cement implantation syndrome is a potentially severe complication that can occur during both cemented and uncemented arthroplasty. Moreover, the occurrence of bone cement implantation syndrome is not dependent on the use of cement. However, the severity does seem to have an association with the fixation method.

Study context

Population
Patients undergoing arthroplasty (hip, knee, shoulder; cemented or uncemented)85 studies
Outcome
Incidence of and risk factors for bone cement implantation syndrome
Methodological detailsPRISMA-ScR Checklist, Literature search in PubMed, Cochrane, and Embase
  • PRISMA-ScR Checklist
  • Literature search in PubMed, Cochrane, and Embase

Main finding

As reported in the abstract

Incidence of bone cement implantation syndrome

Cemented hip arthroplasty

15.4% to 46.7%

Cemented knee arthroplasty

27.5% to 70.7%

Shoulder arthroplasty

16.2%

Uncemented hip arthroplasty

0.0% to 21.8%

Original publication

Bone cement implantation syndrome: a scoping review. Br J Anaesth. Published 8 July 2025. doi:10.1016/j.bja.2025.05.041

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