Perioperative medicine & outcomes
Can perioperative pCO2 gaps predict complications in patients undergoing major elective abdominal surgery randomized to goal-directed therapy or standard care? A secondary analysis
Authors' conclusion
In our study, pCO2 gap was a poor predictor of major postoperative complications at all selected time points.
Study context
- Population
- Patients undergoing high-risk elective abdominal surgery randomised to goal-directed therapy (GDT) or standard care
- Participants
- 464 patients
- Comparison
- Complications vs No complications
- Primary endpoint
- Prediction of postoperative complications by perioperative pCO2 gaps (venous–arterial CO2 pressure difference) at 4 time points
- Follow-up
- 30 days
Primary result
As reported in the abstract
pCO2 gap at end of surgery · end of surgery
P = 0.005
- AUC for predicting complications from pCO2 gaps at all time points
- between 0.5 and 0.6
Further findings
Correlation between ScvO2 and pCO2 gaps · all time points
- Weak correlation, ρ between - 0.40 and - 0.29, p < 0.001
pCO2 gap, GDT vs standard care · all selected time points
- No difference between GDT and standard care at any time point
Original publication
Can perioperative pCO2 gaps predict complications in patients undergoing major elective abdominal surgery randomized to goal-directed therapy or standard care? A secondary analysis. J Clin Monit Comput. Published 22 January 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →