Hemodynamics, fluids & transfusion
Effect of using hypotension prediction index versus conventional goal-directed haemodynamic management to reduce intraoperative hypotension in non-cardiac surgery: A randomised controlled trial
Primary resultResult — go to the resultMedian difference −0.41 mmHg 95% CI −0.69 to −0.10Authors' conclusion
The current randomised controlled trial results suggest that using the hypotension prediction index independently lowered the cumulative amount of intraoperative hypotension during major non-cardiac surgery.
Study context
- Population
- Adults undergoing major non-cardiac surgery under GA
- Participants
- 64 adults
- Comparison
- HPI combined with conventional GDT vs conventional GDT
- Primary endpoint
- Time-weighted average of the areas under the threshold
Methodological detailssingle-centre
- Single-centre
Primary result
As reported in the abstract
Median difference
−0.41 mmHg
95% CI −0.69 to −0.10
P = 0.005
By group
HPI vs FloTrac
median difference −0.41 mmHg (95% CI −0.69 to −0.10); P = 0.005
Secondary outcomes
Norepinephrine administration
P = 0.045
Volumes of fluid and blood products
- No significant differences between groups
Original publication
Effect of using hypotension prediction index versus conventional goal-directed haemodynamic management to reduce intraoperative hypotension in non-cardiac surgery: A randomised controlled trial. J Clin Anesth. Published 30 November 2023. doi:10. 1016/ j. jclinane. 2023. 111348
Composed by AI from the published abstract and checked against it. How Briefs are made →