Hemodynamics, fluids & transfusion

Effect of using hypotension prediction index versus conventional goal-directed haemodynamic management to reduce intraoperative hypotension in non-cardiac surgery: A randomised controlled trial

J Clin AnesthPublished Randomised controlled trial

Primary resultResult — go to the resultMedian difference −0.41 mmHg 95% CI −0.69 to −0.10

Authors' conclusion

The current randomised controlled trial results suggest that using the hypotension prediction index independently lowered the cumulative amount of intraoperative hypotension during major non-cardiac surgery.

Study context

Population
Adults undergoing major non-cardiac surgery under GA
Participants
64 adults
Comparison
HPI combined with conventional GDT vs conventional GDT
Primary endpoint
Time-weighted average of the areas under the threshold
Methodological detailssingle-centre
  • Single-centre

Primary result

As reported in the abstract

Median difference

−0.41 mmHg

95% CI −0.69 to −0.10

P = 0.005

By group

HPI vs FloTrac
median difference −0.41 mmHg (95% CI −0.69 to −0.10); P = 0.005

Secondary outcomes

Norepinephrine administration

P = 0.045

Volumes of fluid and blood products

No significant differences between groups

Original publication

Effect of using hypotension prediction index versus conventional goal-directed haemodynamic management to reduce intraoperative hypotension in non-cardiac surgery: A randomised controlled trial. J Clin Anesth. Published 30 November 2023. doi:10.1016/j.jclinane.2023.111348

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