Organ support & nutrition

Capillary refill time assessment after fluid challenge in patients on venoarterial extracorporeal membrane oxygenation: A retrospective study

J Crit CarePublished Retrospective diagnostic accuracy study

Authors' conclusion

In patients treated with VA-ECMO index capillary refill time is a reliable tool to assesses fluid responsiveness.

Study context

Population
Patients on VA-ECMO in a cardiac surgery ICU receiving a fluid challenge44% post-cardiotomy cardiogenic shock
Participants
27 patients
Comparison
CRT before vs after fluid challenge in responders vs non-responders
  • Respondersn = 13
  • Non-respondersn = 14reference
Outcome
Usefulness of CRT to assess response to fluid challenge
Methodological detailssingle-centre
  • Single-centre

Performance

As reported in the abstract

Index CRT before vs after fluid challenge; diagnostic performance of CRT variation
Test or modelValueAfter fluid challengep
Respondersmedian 1.7 (IQR 1.5–2.1) s1.2 [1; 1.3] sp = 0.01
Non-respondersmedian 1.4 (IQR 1.1–2.5) s1.6 [0.9; 1.9] sp = 0.22

Value

Respondersmedian 1.7 (IQR 1.5–2.1) s
Non-respondersmedian 1.4 (IQR 1.1–2.5) s

After fluid challenge

Responders1.2 [1; 1.3] s
Non-responders1.6 [0.9; 1.9] s

p

Respondersp = 0.01
Non-respondersp = 0.22
CRT variation AUC (p = 0.10)
0.68
Sensitivity
79% (95% CI 52-92)
Specificity
69% (95% CI 42-87)
Threshold
23%

Original publication

Capillary refill time assessment after fluid challenge in patients on venoarterial extracorporeal membrane oxygenation: A retrospective study. J Crit Care. Published 11 March 2024. doi:10.1016/j.jcrc.2024.154770

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