Capillary refill time assessment after fluid challenge in patients on venoarterial extracorporeal membrane oxygenation: A retrospective study
Authors' conclusion
In patients treated with VA-ECMO index capillary refill time is a reliable tool to assesses fluid responsiveness.
Study context
- Population
- Patients on VA-ECMO in a cardiac surgery ICU receiving a fluid challenge44% post-cardiotomy cardiogenic shock
- Participants
- 27 patients
- Comparison
- CRT before vs after fluid challenge in responders vs non-responders
- Respondersn = 13
- Non-respondersn = 14reference
- Outcome
- Usefulness of CRT to assess response to fluid challenge
Methodological detailssingle-centre
- Single-centre
Performance
As reported in the abstract
Index CRT before vs after fluid challenge; diagnostic performance of CRT variation
| Test or model | Value | After fluid challenge | p |
|---|---|---|---|
| Responders | median 1.7 (IQR 1.5–2.1) s | 1.2 [1; 1.3] s | p = 0.01 |
| Non-responders | median 1.4 (IQR 1.1–2.5) s | 1.6 [0.9; 1.9] s | p = 0.22 |
Value
Respondersmedian 1.7 (IQR 1.5–2.1) s
Non-respondersmedian 1.4 (IQR 1.1–2.5) s
After fluid challenge
Responders1.2 [1; 1.3] s
Non-responders1.6 [0.9; 1.9] s
p
Respondersp = 0.01
Non-respondersp = 0.22
- CRT variation AUC (p = 0.10)
- 0.68
- Sensitivity
- 79% (95% CI 52-92)
- Specificity
- 69% (95% CI 42-87)
- Threshold
- 23%
Original publication
Capillary refill time assessment after fluid challenge in patients on venoarterial extracorporeal membrane oxygenation: A retrospective study. J Crit Care. Published 11 March 2024. doi:10. 1016/ j. jcrc. 2024. 154770
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