Neuroanesthesia & neurocritical care

Cardiac dysfunction in patients affected by subarachnoid haemorrhage affects in-hospital mortality: A systematic review and metanalysis

Eur J AnaesthesiolPublished Systematic review of observational studies

Pooled result · In-hospital mortalityResult — go to the resultOdds ratio 2.69 CI 1.64–4.41

Authors' conclusion

About one in five patients with SAH develops cardiac dysfunction, which seems to be associated with higher in-hospital mortality.

Study context

Population
Adults with subarachnoid haemorrhage (SAH) admitted to intensive care with echocardiography findings
Participants
3,511 adults · 23 studies
Comparison
Cardiac dysfunction vs no cardiac dysfunction
  • Cardiac dysfunctionn = 725
Outcome
In-hospital mortality and poor neurological outcome by presence or absence of cardiac dysfunction
Methodological detailsGRADE assessment
  • GRADE assessment

Pooled result

In-hospital mortality

Odds ratio

2.69

CI 1.64–4.41

P < 0.001

Cardiac dysfunction vs No cardiac dysfunction
OR 2.69 (CI 1.64–4.41); P < 0.001

As reported in the abstract

Further pooled results

Prevalence of cardiac dysfunction
21% · 725
Prevalence of cardiac dysfunction — Reported as regional wall motion abnormality in most studies
63%

Original publication

Cardiac dysfunction in patients affected by subarachnoid haemorrhage affects in-hospital mortality: A systematic review and metanalysis. Eur J Anaesthesiol. Published 12 April 2023. doi:10.1097/eja.0000000000001829

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