Neuroanaesthesia & neurocritical care
The association between early core body temperature in ICU and mortality in spontaneous subarachnoid haemorrhage: a binational registry study
Authors' conclusion
In critically ill SAH patients, D1 core temperature had a U-shaped association with in-hospital mortality. Further research should determine whether temperature variation is a modifiable risk factor in this population.
Study context
- Population
- Adults (≥18 years) with spontaneous subarachnoid haemorrhage (SAH) admitted to ICU between January 2018 and June 2024adults with SAH admitted to ICU, included
- Participants
- 7,567 adults
- Exposure
- Day-one (D1) core body temperature (TANZ, the highest (THI), TLO) and in-hospital mortality; temperatures below or above the range of lowest observed mortality vs within it
- Outcome
- In-hospital mortality
Methodological detailsbinational registry, Australian and New Zealand Intensive Care Society Adult Patient Database, generalised linear models with natural cubic splines and covariate adjustment
- Binational registry
- Australian and New Zealand Intensive Care Society Adult Patient Database
- Generalised linear models with natural cubic splines and covariate adjustment
Main finding
As reported in the abstract
Odds ratio (95% CI)
TANZ below 35.8-38.2 °C vs TANZ 35.8-38.2 °Cmortality increased below the range of lowest observed mortality
1.55(1.34–1.79)
THI below 36.8-38.2 °C vs THI 36.8-38.2 °Cmortality increased below the range of lowest observed mortality
1.42(1.20–1.69)
TLO below 36.1-37.8 °C vs TLO 36.1-37.8 °Cmortality increased below the range of lowest observed mortality
1.38(1.19–1.60)
THI above 36.8-38.2 °C vs THI 36.8-38.2 °Cmortality increased above the optimal range of THI
1.47(1.19–1.80)
- Overall in-hospital mortality
- 17% (n = 1,304)
- Lowest observed mortality at TANZ
- 35.8-38.2 °C
- Lowest observed mortality at THI
- 36.8-38.2 °C
- Lowest observed mortality at TLO
- 36.1-37.8 °C
Observational data: associations, not effects.
Further findings
Day-one core temperatures (descriptive) · first 24 ICU hours
Original publication
The association between early core body temperature in ICU and mortality in spontaneous subarachnoid haemorrhage: a binational registry study. Anaesth Crit Care Pain Med. Published 6 October 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →