Cardiac arrest & resuscitation

Cardiac power output is associated with cardiovascular related mortality in the intensive care unit (ICU) in post-cardiac arrest patients

ResuscitationPublished Retrospective cohort study

Authors' conclusion

In post-CA patients, the 8-hour CPO is an independent factor associated with ICU cardiovascular-related mortality.

Study context

Population
Adult comatose survivors of cardiac arrest admitted to a university hospital ICU, excluding ECPR, ECMO or intra-aortic balloon pump61.8% OHCA
Participants
217 survivors
Exposure
Survivors vs non-survivors
  • Non-survivorsn = 142
Outcome
Association of CPO with early ICU mortality and with mortality related to post-CA cardiovascular failure
Follow-up
First 72 hours after ROSC
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

CPO, survivors vs non-survivors; CPO and CV-related mortality
Cardiac power output (CPO) significantly different between survivors and non-survivors only at +8 h after cardiac arrest (CA)
p = 0.0042
8-h CPO independently associated with CV-related mortality (multivariable analysis)
p = 0.007

Observational data: associations, not effects.

Further findings

ICU death
142 (65.4%)
Death from neurological injury
99 (69.7%)
Death from CV-related causes
43 (30.3%)

Original publication

Cardiac power output is associated with cardiovascular related mortality in the ICU in post-cardiac arrest patients. Resuscitation. Published 27 November 2023. doi:10.1016/j.resuscitation.2023.110062

Composed by AI from the published abstract and checked against it. How Briefs are made →

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