Cardiac arrest & resuscitation

Intra-aortic balloon pump in patients with extracorporeal cardiopulmonary resuscitation after cardiac arrest caused by acute coronary syndrome

ResuscitationPublished Secondary analysis of the SAVE-J II registry study

Authors' conclusion

IABP use in patients with OHCA with ACS who received ECPR is not associated with 30-day survival.

Study context

Population
Patients with out-of-hospital cardiac arrest (OHCA) caused by acute coronary syndrome (ACS) who received extracorporeal cardiopulmonary resuscitation (ECPR)of 2,157 registered
Participants
877 patients
Comparison
Intra-aortic balloon pump (IABP) vs no IABP
  • IABPn = 702
  • non-IABPn = 175reference
Primary endpoint
30-day survival
Follow-up
30 days
Methodological detailsretrospective, multicentre, 36 institutions in Japan
  • Retrospective
  • Multicentre
  • 36 institutions in Japan

Primary result

As reported in the abstract

No significant difference in 30-day survival with IABP use (multivariable logistic regression: OR 1.37, 95% CI 0.91-2.07)
p = 0.13

Further findings

30-day survival, subgroups (no PCI; multivessel stenosis)

30-day survival associated with IABP use in patients without PCI and with multivessel coronary stenosis

Original publication

Intra-aortic balloon pump in patients with extracorporeal cardiopulmonary resuscitation after cardiac arrest caused by acute coronary syndrome. Resuscitation. Published 13 December 2023. doi:10.1016/j.resuscitation.2023.110091

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