Cardiac arrest & resuscitation

Intra-aortic balloon pump use in out-of-hospital cardiac arrest patients who underwent extracorporeal cardiopulmonary resuscitation

ResuscitationPublished Retrospective cohort study

Main finding · Favourable neurological outcome among survivorsResult — go to the resultAdjusted odds ratio 1.22 95% CI 0.79–1.89

Authors' conclusion

The use of IABP in patients with OHCA who underwent ECPR was associated with 30-day survival. Among survived patients, there was no significant association between IABP use and 30-day neurological outcome.

Study context

Population
Adults (≥18 years) with out-of-hospital cardiac arrest (OHCA) who underwent ECPR, Japanese OHCA registry, June 2014–December 2019842 matched
Participants
2,135 adults
Exposure
Intra-aortic balloon pump (IABP) vs no IABP after ECPR
  • IABPn = 1,173
Outcome
Favourable neurological outcome in survived patients
Follow-up
30 days
Methodological detailspropensity-score matched, registry-based
  • Propensity-score matched
  • Registry-based

Main finding

Favourable neurological outcome among survivors

Adjusted odds ratio

1.22

95% CI 0.79–1.89

P = 0.36

IABP vs No IABP
aOR 1.22 (95% CI 0.79–1.89); P = 0.36

As reported in the abstract

Observational data: associations, not effects.

Secondary outcomes

OutcomeaOR (95% CI)P value
Survival · 30 days842 matched patients · matched cohort1.98 (1.39–2.83)P < 0.001

Original publication

Intra-aortic balloon pump use in out-of-hospital cardiac arrest patients who underwent extracorporeal cardiopulmonary resuscitation. Resuscitation. Published 5 December 2022. doi:10.1016/j.resuscitation.2022.11.026

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