Central venous catheter-related infection: does insertion site still matter? A French multicentric cohort study
Authors' conclusion
CRBSI incidences rates were similar in the three insertion sites.
Study context
- Population
- Central venous catheter (CVCs) inserted and removed during the same ICU stay, with tips sent for microbiological analysis, 193 intensive care units (ICUs) (REA-REZO), 2018–2022CVCs included
- Participants
- 55,663 cvcs
- Exposure
- CVC insertion site: IJ vs femoral vs SC
- IJn = 30,548
- Femoraln = 14,423
- SCn = 10,692
- Outcome
- Catheter-related bloodstream infection (CRBSI) by CVC insertion site
Methodological detailsnationwide surveillance cohort, 71,314 of 126,997 CVCs not sent for tip culture and excluded
- Nationwide surveillance cohort
- 71,314 of 126,997 CVCs not sent for tip culture and excluded
Main finding
As reported in the abstract
CRBSI incidence (per 1000 CVC days)
P = 0.248
Observational data: associations, not effects.
Further findings
Microorganisms in catheter-related bloodstream infection (CRBSI)
- Coagulase-negative Staphylococci
- 27.9%
- Enterobacterales
- 27.5%
- Non-fermenting Gram-negative Bacilli
- 10.4%
- Candida sp.
- 16.9%
- Staphylococcus aureus
- 16.9%
Original publication
Central venous catheter-related infection: does insertion site still matter? A French multicentric cohort study. Intensive Care Med. Published 17 September 2024. doi:10.
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