Perioperative medicine & outcomes
Central venous catheter tip misplacement: A multicentre cohort study of 8556 thoracocervical central venous catheterisations
Authors' conclusion
In this large prospective multicentre cohort study, performed in the ultrasound-guided era, we demonstrated the incidence of tip misplacements to be 3.7 (3.3-4.1)%.
Study context
- Population
- Patients ≥16 years with jugular or subclavian central venous catheter insertion and post-procedural chest radiography, four hospitalsinsertions in 5587 patients
- Participants
- 8,556 patients
- Outcome
- Incidence of central venous catheter tip misplacement
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Tip misplacement
Any tip misplacement
3.7%
95% CI 3.3–4.1
Major tip misplacement
2.1%
95% CI 1.8–2.4
Observational data: associations, not effects.
Further findings
Variables associated with major tip misplacement (multivariable logistic regression)
- Higher risk: female gender, subclavian vein insertion, number of skin punctures, limited operator experience
- Lower risk: increasing age and height
Tip misplacement by insertion site
- Right internal jugular vein catheterisation had the lowest incidence of minor and major tip misplacement
Original publication
Central venous catheter tip misplacement: A multicentre cohort study of 8556 thoracocervical central venous catheterisations. Acta Anaesthesiol Scand. Published 13 February 2024. doi:10.
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