Cardiothoracic & vascular anesthesia
Central Versus Peripheral Arterial Pressure Monitoring in Patients Undergoing Cardiac Surgery: A Prospective Observational Study
Authors' conclusion
No differences in the norepinephrine dose regimen were found according to the arterial measurement site during cardiac surgery. However, norepinephrine use and length of stay in the ICU were shorter, and adverse events were decreased when central arterial pressure monitoring was used.
Study context
- Population
- Consecutive adults undergoing cardiac surgery with cardiopulmonary bypass (CPB)enrolled and analyzed
- Participants
- 286 adults
- Exposure
- Central vs radial arterial pressure monitoring
- Centraln = 109
- Radialn = 177reference
- Outcome
- Intraoperative amount of norepinephrine administered
Methodological detailspropensity score analysis, consecutive patients, single tertiary academic hospital
- Propensity score analysis
- Consecutive patients
- Single tertiary academic hospital
Main finding
As reported in the abstract
Intraoperative norepinephrine dose regimen
P = 0.519
Observational data: associations, not effects.
Secondary outcomes
Norepinephrine-free hours · POD2
P = 0.034
ICU-free hours · POD2
P = 0.008
| Outcome | Central | Radial | P value |
|---|---|---|---|
| EuroSCORE before adjustment | 7.9 ± 14.0 | 3.8 ± 7.0 | P < 0.001 |
EuroSCORE before adjustment
- After adjustment, similar EuroSCORE and arterial BP levels in both groups
Safety
| Outcome | P value |
|---|---|
| Adverse events | P = 0.007 |
- Adverse events: percentages printed as "67% versus 50%" (order inconsistent with the stated direction)
Adverse events
- Adverse events less frequent in Central than Radial
Original publication
Central Versus Peripheral Arterial Pressure Monitoring in Patients Undergoing Cardiac Surgery: A Prospective Observational Study. J Cardiothorac Vasc Anesth. Published 23 April 2023. doi:10.
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