ICU sedation, delirium & recovery
Cerebral autoregulation-based mean arterial pressure targets and delirium in critically ill adults without brain injury: a retrospective cohort study
Authors' conclusion
We observed that MAPopt targets across patients were highly variable, but did not observe an association with the incidence of delirium.
Study context
- Population
- Critically ill adults without brain injury: shock of any etiology and/or respiratory failure requiring invasive mechanical ventilation, without a neurologic admitting diagnosisanalysed
- Participants
- 42 adults
- Outcome
- Optimal MAP (MAPopt) ranges and whether deviations from these targets contribute to intensive care unit (ICU) delirium
Methodological detailsDaily delirium screening; cerebral oximetry and MAP data captured for the first 24 hr from enrolment
- Daily delirium screening; cerebral oximetry and MAP data captured for the first 24 hr from enrolment
Main finding
As reported in the abstract
Blood pressure targets exceeding the 65 mm Hg Surviving Sepsis guidelines
69%
Observational data: associations, not effects.
Original publication
Cerebral autoregulation-based mean arterial pressure targets and delirium in critically ill adults without brain injury: a retrospective cohort study. Can J Anaesth. Published 6 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →