Neuroanesthesia & neurocritical care

Cerebral autoregulation in traumatic brain injury: ultra-low-frequency pressure reactivity index and intracranial pressure across age groups

Crit CarePublished Observational cohort study

Authors' conclusion

The study highlights UL-PRx as a tool for assessing CA and valuable outcome predictor for TBI patients.

Study context

Population
Traumatic brain injury (TBI) patients across age groups
Participants
263 patients
Exposure
Pediatric vs Adult vs ≥ 70 y
Outcome
Predictive power of UL-PRx for outcome (GOSE)
Follow-up
12 months

Main finding

As reported in the abstract

Association of UL-PRx with 12-month outcome

Observational data: associations, not effects.

Further findings

Mortality and unfavorable outcome (Glasgow Outcome Scale Extended (GOSE))

In-hospital mortality
25.9%
12-month mortality
32.7%
Unfavorable outcome at 12 months (GOSE)
60.0%

UL-PRx and CPPopt

UL-PRx associated with CPPopt

Original publication

Cerebral autoregulation in traumatic brain injury: ultra-low-frequency pressure reactivity index and intracranial pressure across age groups. Crit Care. Published 23 January 2024. doi:10.1186/s13054-024-04814-5

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.