Pediatric anesthesia & critical care

Cerebral oxygenation saturation in childhood: difference by age and comparison of two cerebral oximetry algorithms

J Clin Monit ComputPublished Observational study

Authors' conclusion

In pediatric patients undergoing non-cardiac surgery, rSO2 values differed across the three age groups, and the pattern of these differences varied between the two oximeters employing different algorithms.

Study context

Population
Children undergoing non-cardiac surgery
Participants
78 children
Exposure
Infants vs toddlers vs schoolchildren; tNIRS-1 vs INVOS 5100C
  • Infantsn = 26
  • Toddlersn = 26
  • Schoolchildrenn = 26
Outcome
Regional cerebral oxygen saturation (rSO2) by age group, measured with tNIRS-1 (time-resolved spectroscopy) and INVOS 5100C
Methodological detailscomparison of two cerebral oximeters
  • Comparison of two cerebral oximeters

Main finding

As reported in the abstract

rSO2 by age group
  • INVOS 5100C: rSO2 significantly lower in infants than in other patients
  • tNIRS-1: rSO2 higher in toddlers than in other groups

Observational data: associations, not effects.

Further findings

Correlation between tNIRS-1 and INVOS 5100C rSO2

Moderate correlation (r)
0.41
INVOS 5100C values approximately higher, with ceiling effect
20%

Physiological factors influencing rSO2

INVOS 5100C values affected by BP; tNIRS-1 values affected by MAC of sevoflurane

Original publication

Cerebral oxygenation saturation in childhood: difference by age and comparison of two cerebral oximetry algorithms. J Clin Monit Comput. Published 4 February 2024. doi:10.1007/s10877-023-01124-z

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