Pediatric anesthesia & critical care
Regional oxygen saturation measured by two different oximetry monitors in infants and children undergoing living donor liver transplantation with bilirubin measurements: A prospective observational study
Authors' conclusion
Oximetry devices emitting light at >2 wavelengths may overcome interference from hyperbilirubinemia providing higher rSO2 readings.
Study context
- Population
- Infants and children undergoing living donor liver transplantation, March 2019 to September 2020median age 27 months
- Participants
- 33 infants
- Exposure
- ForeSight Elite vs INVOS 5100C
- Outcome
- Cerebral and somatic regional tissue oxygen saturation (rSO2) readings and bilirubin interference
Main finding
As reported in the abstract
Cerebral and somatic rSO2 (linear mixed effects model)
- Cerebral rSO2 differed by time
- p = .031
- Cerebral rSO2 differed by device
- p < .001
- Cerebral rSO2 differed by bilirubin concentrations
- p = .007
- Cerebral rSO2 not different by hemoglobin
- p = .347
- Cerebral rSO2 not different by SpO2
- p = .882
- Cerebral rSO2 not different by PaCO2
- p = .146
- Somatic rSO2 differed by device
- p < .001
- Somatic rSO2 differed by bilirubin concentrations
- p = .023
- Somatic rSO2 not different by time
- p = .074
- Somatic rSO2 not different by hemoglobin
- p = .954
- Somatic rSO2 not different by SpO2
- p = .108
- Somatic rSO2 not different by PaCO2
- p = .775
Observational data: associations, not effects.
Further findings
Agreement of cerebral rSO2 between both devices (Bland-Altman)
- Mean absolute bias
- 21.73%
- 95% limits of agreement
- −10.21 to 53.67
Agreement of somatic rSO2 between both devices (Bland-Altman)
- Mean absolute bias
- 19.52%
- 95% limits of agreement
- −29.51 to 68.54
Original publication
Regional oxygen saturation measured by two different oximetry monitors in infants and children undergoing living donor liver transplantation with bilirubin measurements: A prospective observational study. Paediatr Anaesth. Published 11 November 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →