Respiratory failure & ventilation
Changes in internal jugular vein respiratory variation during tidal volume challenge predict volume responsiveness in lumbar surgery under protective ventilation: a prospective cohort study
Authors' conclusion
In patients undergoing posterior lumbar surgery with low Vt ventilation, changes in IJVV during a TVC effectively predict volume responsiveness and are more reliable than IJVV, PPV, and SVV in this surgical context.
Study context
- Population
- Patients undergoing posterior lumbar surgery in the prone position ventilated with low Vt (6 ml kg-1 predicted body weight (PBW))31 volume responsive
- Participants
- 61 patients
- Exposure
- ΔIJVV6-8 during tidal volume challenge vs IJVV6, PPV6 and SVV6 for predicting volume responsiveness
- Outcome
- Ability of ΔIJVV6-8 to predict volume responsiveness (ΔCItrend ≥ 8% during Trendelenburg maneuver)
Methodological detailsdiagnostic accuracy, single operating-room setting
- Diagnostic accuracy
- Single operating-room setting
Main finding
As reported in the abstract
Prediction of volume responsiveness
| Group | AUC | AUC 95% CI | AUC P | Sensitivity | Specificity |
|---|---|---|---|---|---|
| ΔIJVV6-8 | 0.96 | 0.88-0.99 | P < 0.001 | 96.77% | 86.67% |
ΔIJVV6-8
AUC0.96
AUC 95% CI0.88-0.99
AUC PP < 0.001
Sensitivity96.77%
Specificity86.67%
- ΔIJVV6-8 vs IJVV6: P = 0.04 — AUC significantly higher for ΔIJVV6-8
- ΔIJVV6-8 vs PPV6: P < 0.001 — AUC significantly higher for ΔIJVV6-8
- ΔIJVV6-8 vs SVV6: P = 0.01 — AUC significantly higher for ΔIJVV6-8
Observational data: associations, not effects.
Original publication
Changes in internal jugular vein respiratory variation during tidal volume challenge predict volume responsiveness in lumbar surgery under protective ventilation: a prospective cohort study. J Intensive Care. Published 30 September 2025. doi:10.
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