Perioperative medicine & outcomes

Characterisation of older patients that require, but do not undergo, emergency laparotomy: a multicentre cohort study

Br J AnaesthPublished Prospective cohort study

Authors' conclusion

This study reports that the NoLap patient population present significant medical challenges because of their extreme levels of comorbidity, frailty, and physiology. Despite these complexities a fifth remained alive at 90 days.

Study context

Population
Older adults (≥65 yr) admitted with a condition treatable by emergency laparotomy but not operated on, 64 UK surgical centres, 2021
Participants
750 adults · 64 UK centres
Outcome
90-day mortality
Follow-up
90 days
Methodological detailsmulticentre, consecutive recruitment
  • Multicentre
  • Consecutive recruitment

Main finding

As reported in the abstract

Mortality

90-day mortality

79%

Observational data: associations, not effects.

Further findings

Patient characteristics

Female
452 patients, 60%
Median age (IQR), yr
83.0 (77.0-88.8)
Frail
523 patients, 70%
Severe comorbidity
750 patients, 100%
CT scanning
99%

Commonest diagnoses

Perforation
26%
Small bowel obstruction
17%
Ischaemic bowel
13%

Place of death and survivor destination · 90 days

Died in hospital
77%
Survived to 90 days
21%
Survivors returned home with increased care requirements
77%
Ischaemic bowel patients died early

Original publication

Characterisation of older patients that require, but do not undergo, emergency laparotomy: a multicentre cohort study. Br J Anaesth. Published 4 October 2024. doi:10.1016/j.bja.2024.07.009

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