Perioperative medicine & outcomes

Beyond high‐risk: analysis of the outcomes of extreme‐risk patients in the National Emergency Laparotomy Audit

AnaesthesiaPublished Retrospective cohort study

Authors' conclusion

These data underscore the need for a differentiated approach when discussing risk with patients at extreme risk of mortality following an emergency laparotomy.

Study context

Population
All patients enrolled in the National Emergency Laparotomy Audit (NELA) database, December 2012 to 20205,193 (3.2%) extreme risk
Participants
161,337 patients
Exposure
Extreme-risk vs high-risk emergency laparotomy patients
  • 50-59n = 2,437
  • 60-69n = 1,484
  • 70-79n = 840
  • 80+n = 423
Outcome
90-day survival
Follow-up
90 days
Methodological detailsnational audit database
  • National audit database

Main finding

As reported in the abstract

Observational data: associations, not effects.

Further findings

OutcomeValuesP value
Hospital LOS50-59 median 26 (IQR [range] 16-43 [0-271]) days · 80+ median 35 (IQR [range] 21-56 [0-368]) days · High-risk median 17 (IQR [range] 10-30 [0-1136]) days
Unplanned return to operating theatreExtreme-risk 11% · High-risk 8%
Elective admissionExtreme-risk vs High-risk · significantly more likely in extreme-riskP < 0.001

Original publication

Beyond high‐risk: analysis of the outcomes of extreme‐risk patients in the National Emergency Laparotomy Audit. Anaesthesia. Published 29 September 2023. doi:10.1111/anae.16130

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