Characteristics and outcomes of ECMO cannula-related infections: a European multicenter retrospective study
Authors' conclusion
ECMO-CRIs are frequently associated with BSI and frequently polymicrobial. Duration of antimicrobial treatment for ECMO-CRI ≤ 8 days does not seem to be associated with an increased risk of recurrence or death, as compared to longer treatment.
Study context
- Population
- ICU patients with ECMO cannula-related infection (clinical suspicion plus positive bacterial sample of ECMO-cannulation site), 12 European ICUs
- Participants
- 109 patients · 12 European ICUs
- Exposure
- Antibiotic course ≤ 8 days vs > 8 days
- Outcome
- ECMO-CRI characteristics and outcomes
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Concomitant positive blood culture with same pathogen
78
Polymicrobial episodes
42%
ICU mortality
51%
Observational data: associations, not effects.
Secondary outcomes
Infection recurrence
- Recurrence rate
- 13%
Risk factors for death
- Concomitant bloodstream infection with same pathogen and septic shock
Antibiotic duration and outcome
- Similar infection recurrence rate and outcomes (incl. mortality) with ≤ 8 days vs > 8 days
Original publication
Characteristics and outcomes of ECMO cannula-related infections: a European multicenter retrospective study. Ann Intensive Care. Published 20 March 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →