ICU sedation, delirium & recovery
Characteristics and outcome of COVID-19 patients admitted to the ICU: a nationwide cohort study on the comparison between the consecutive stages of the COVID-19 pandemic in the Netherlands, an update
Authors' conclusion
The results show variation in mortality rates among critically ill COVID-19 patients across the calendar time periods that is not explained by differences in case-mix and ICU occupancy rates or by varying proportions of patients with COVID-19 as main reason for ICU admission.
Study context
- Population
- All COVID-19 patients admitted to an ICU in the Netherlands (National Intensive Care Evaluation (NICE) registry), February 2020-January 31, 2023
- Exposure
- Consecutive pandemic periods after the first wave vs first wave
- Outcome
- In-hospital mortality
Methodological detailsregistry-based
- Registry-based
Main finding
As reported in the abstract
Each group vs period 1Adjusted odds ratio (95% CI)
Period 6
1.01(0.88–1.16)
Period 9
0.52(0.41–0.66)
Observational data: associations, not effects.
Further findings
Proportion of SARS-CoV-2 positive patients with COVID-19 as main reason for ICU admission
- Initial upsurge of the third wave
- 88.2%
- Periods thereafter
- 51.7%, 37.3%, and 41.9%
In-hospital mortality restricted to patients with COVID-19 as main reason for ICU admission
- Restriction did not modify the results on mortality
Original publication
Characteristics and outcome of COVID-19 patients admitted to the ICU: a nationwide cohort study on the comparison between the consecutive stages of the COVID-19 pandemic in the Netherlands, an update. Ann Intensive Care. Published 16 January 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →