Characterization of Speech and Language Deficits in the Postanesthesia Care Unit: A Novel, Qualitative Cognitive Assessment
Main finding · Speech-language and cognitive scores, pre- vs postoperative (PACU)Result — go to the resultF[1-46] 21.7Authors' conclusion
The PACU-SLA revealed lower fluency (hypophonia) with relatively intact comprehension, naming, and repetition, during recovery from general anesthesia.
Study context
- Population
- Patients undergoing GA for noncardiac and nonneurologic elective surgeries
- Participants
- 48 patients
- Exposure
- AB vs AA
- ABn = 25
- AAn = 23reference
- Outcome
- Speech-language and cognitive scores, pre- vs postoperative (PACU)
- Follow-up
- ≥30 minutes after PACU arrival, before PACU discharge
Methodological detailspre- vs postoperative paired assessment, randomised Telephonic Montreal Cognitive Assessment (t-MoCA) version allocation
- Pre- vs postoperative paired assessment
- Randomised t-MoCA version allocation
Main finding
As reported in the abstract
F[1-46]
21.7
P < 0.001
- Narrative-production (expressive fluency, 9-point) median [25th-75th], preoperative
- 9[9-9]
- Narrative-production median [25th-75th], postoperative (P < .001)
- 7[7-8]
- Verbal fluency total words median [25th-75th], preoperative
- 23[12.5-33.5]
- Verbal fluency total words median [25th-75th], postoperative (P < .001)
- 16.5[9.5-26.5]
- Sentence repetition (4-point) median [25th-75th], preoperative
- 4[3-4]
- Sentence repetition median [25th-75th], postoperative (P = .04)
- 4[3-4]
Observational data: associations, not effects.
Further findings
| Outcome | F[1-46] | P value |
|---|---|---|
| t-MoCA episodic memory (delayed recall)Decreased in AB | 48.6 | P < 0.001 |
Postoperative changes by preoperative cognitive status (pMCI n = 9; normal n = 39) (subgroup)
- Verbal fluency, both groups changed: F[1-46] = 6.97, P = .01
- Narrative production, both groups changed: F[1-46] = 5.51, P = .02
Original publication
Characterization of Speech and Language Deficits in the Postanesthesia Care Unit: A Novel, Qualitative Cognitive Assessment. Anesth Analg. Published 25 March 2024. doi:10.
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