ICU sedation, delirium & recovery

Development of Postanesthesia Care Unit Delirium Is Associated with Differences in Aperiodic and Periodic Alpha Parameters of the Electroencephalogram during Emergence from General Anesthesia: Results from a Prospective Observational Cohort Study

AnesthesiologyPublished Secondary analysis of a prospective observational cohort study

Authors' conclusion

Increased alpha-band power during emergence in patients who did not develop perioperative neurocognitive disorders can be traced back to an increase in oscillatory alpha activity and an overall increase in aperiodic broadband power.

Study context

Population
Patients with intraoperative EEG recordings during emergence from GA
Participants
32 vs 137
Comparison
Intraoperative EEG during emergence in patients with vs without perioperative neurocognitive disorders (PACU delirium)
  • With perioperative neurocognitive disordersn = 32
  • Without perioperative neurocognitive disordersn = 137reference
Methodological detailspost hoc
  • Post hoc

Primary result

As reported in the abstract

Alpha-band power during emergence, with vs without perioperative neurocognitive disorders

Difference in median absolute alpha-band power, first third of emergence (highest value; AUC 0.74 [0.65; 0.82])

8.53 decibels

Difference in medians, relative alpha-band power, second third of emergence (best relative separation; AUC 0.70 [0.61; 0.79])

7.71%

Original publication

Development of Postanesthesia Care Unit Delirium Is Associated with Differences in Aperiodic and Periodic Alpha Parameters of the Electroencephalogram during Emergence from General Anesthesia: Results from a Prospective Observational Cohort Study. Anesthesiology. Published 10 October 2023. doi:10.1097/aln.0000000000004797

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