Clinical characteristics and short-term outcomes of patients with critical acute pulmonary embolism requiring extracorporeal membrane oxygenation: from the COMMAND venous thromboembolism (VTE) Registry-2
Authors' conclusion
The current large real-world VTE registry in Japan revealed clinical features and outcomes of critical acute PE requiring ECMO in the current era
Study context
- Population
- Patients with acute symptomatic pulmonary embolism (PE) requiring extracorporeal membrane oxygenation (ECMO), COMMAND VTE Registry-2, Japanof 2035 with acute PE
- Participants
- 76 patients
- Exposure
- Surgical intervention vs Catheter intervention vs Thrombolytic therapy vs Anticoagulation only
- Surgical interventionn = 16
- Catheter interventionn = 16
- Thrombolytic therapyn = 16
- Anticoagulation onlyn = 28
- Outcome
- All-cause death
- Follow-up
- 30 days
Methodological detailsphysician-initiated, multicentre, registry
- Physician-initiated
- Multicentre
- Registry
Main finding
As reported in the abstract
30-day incidence of all-cause death, all PE-related
30.3%
Cardiac arrest or circulatory collapse at diagnosis
88.2%
Observational data: associations, not effects.
Further findings
All-cause death by management strategy · 30 days
Safety
- 30-day incidence of major bleeding
- 54.0%
- Surgery-related bleeding
- 22.4%
- Vast majority procedure site-related and surgery-related bleeding
Original publication
Clinical characteristics and short-term outcomes of patients with critical acute pulmonary embolism requiring extracorporeal membrane oxygenation: from the COMMAND VTE Registry-2. J Intensive Care. Published 5 November 2024. doi:10.
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