Clinical features and outcomes of peripartum obstetric patients admitted to the intensive care unit: A nationwide inpatient database in Japan
Authors' conclusion
This nationwide study highlights hemorrhage as the primary cause of obstetric ICU admissions in Japan, with an all cause in-hospital mortality of 1.1%.
Study context
- Population
- Peripartum obstetric patients admitted to the intensive care unit (ICU) who delivered during hospitalization or within one week before admission, Japanese Diagnosis Procedure Combination database, July 2010 to March 2022
- Participants
- 8,184 patients · 195 institutions
- Exposure
- Survivors vs non-survivors
- Outcome
- Causes of ICU admission, interventions and in-hospital mortality
Methodological detailsnationwide inpatient database
- Nationwide inpatient database
Main finding
As reported in the abstract
- Hemorrhage as cause of ICU admission
- 52.6%
- Hypertensive disorders of pregnancy as cause of ICU admission
- 16.7%
- Blood transfusions
- 71.5%
- Mechanical ventilation
- 28.0%
- Transcatheter arterial embolization
- 18.0%
- Overall in-hospital mortality
- 1.1%
Observational data: associations, not effects.
Further findings
Demographics
- Median age, years (IQR 30-38)
- 34
- Cesarean delivery
- 53.2%
Non-survivors vs survivors
- Non-survivors had a lower proportion of hemorrhage-related cases but higher prevalence of amniotic fluid embolism, cardiovascular and cerebrovascular disease, infection, pulmonary disease, trauma, and suicide
Original publication
Clinical features and outcomes of peripartum obstetric patients admitted to the intensive care unit: A nationwide inpatient database in Japan. Crit Care. Published 14 August 2025. doi:10.
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