Pediatric anesthesia & critical care
Clinical Impact of Specific Extraocular Muscle Manipulation and the Oculocardiac Reflex on Postoperative Vomiting in Pediatric Strabismus Surgery: A Multicenter, Observational Study
Authors' conclusion
However, the oculocardiac reflex was not associated with postoperative vomiting in pediatric strabismus surgery.
Study context
- Population
- Children aged < 18 years without major comorbidities undergoing strabismus surgery, 3 institutions
- Participants
- 3,152 children
- Exposure
- Inferior oblique muscle manipulation vs none
- With inferior oblique muscle manipulationn = 795
- Without inferior oblique muscle manipulationn = 2,357reference
- Outcome
- Postoperative vomiting or antiemetic medication usage
- Follow-up
- Within 24 h postsurgery or by discharge
Methodological detailsmulticentre, multilevel logistic regression
- Multicentre
- Multilevel logistic regression
Main finding
As reported in the abstract
With IO manipulation vs Without IO manipulationEstimate (95% CI)P value
With IO manipulation vs Without IO manipulation
unadjusted OR 1.57(1.21–2.05)
P = 0.001Adjusted for confounders and surgeon-related variance
aOR 1.58(1.15–2.18)
P = 0.005Observational data: associations, not effects.
Further findings
Oculocardiac reflex and postoperative vomiting
| aOR (95% CI) | P value | ||
|---|---|---|---|
| Oculocardiac reflex | 1.06 (0.76–1.48) | P = 0.73 | |
| 0.512Adjusted odds ratio (log scale) |
Original publication
Clinical Impact of Specific Extraocular Muscle Manipulation and the Oculocardiac Reflex on Postoperative Vomiting in Pediatric Strabismus Surgery: A Multicenter, Observational Study. Paediatr Anaesth. Published 30 November 2024. doi:10.
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