Pediatric anesthesia & critical care
Effect of Ice Slush on Reducing the Oculocardiac Reflex During Strabismus Surgery
Primary result · Newcombe methodResult — go to the resultAbsolute risk difference −31.0% 95% CI −49.4 to −11.0Authors' conclusion
IS on the ocular surface causing local hypothermia is a promising and easily accessible method to reduce the overall OCR, which can improve the safety of strabismus surgery.
Study context
- Population
- Patients with concomitant strabismus scheduled for lateral rectus recession under GA
- Participants
- 58 patients
- Comparison
- Ice slush vs room-temperature sterile saline before surgery
- Ice slush (IS)n = 29
- Controln = 29reference
- Primary endpoint
- Incidence of overall oculocardiac reflex (OCR) (HR decrease >15% from baseline in any stage) during all stages of surgery
Methodological detailsprospective, double-blind
- Prospective
- Double-blind
Primary result
Newcombe method
Absolute risk difference
−31.0%
95% CI −49.4 to −11.0
P < 0.001
Events by treatment group
IS vs Control
absolute risk difference −31.0% (95% CI −49.4 to −11.0); P < 0.001
As reported in the abstract
Original publication
Effect of Ice Slush on Reducing the Oculocardiac Reflex During Strabismus Surgery. Anesth Analg. Published 2 November 2022. doi:10.
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